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Dynamic imaging of cerebral blood flow using laser speckle
A method for dynamic, high-resolution cerebral blood flow (CBF) imaging is presented in this article. By illuminating the cortex with …
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Transport-based image reconstruction in turbid media with small source–detector separations
We demonstrate a new method for imaging through several millimeters of a turbid sample with a resolution of approximately 100 µm by …
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Gene inactivation by multiphoton-targeted photochemistry
Multiphoton-targeted photochemistry was used to selectively inactivate the expression of genes in vertebrate cells. A membrane …
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A pulsed finite-difference time-domain (FDTD) method for calculating light scattering from biological cells over broad wavelength ranges
We combine the finite-difference time-domain method with pulse response techniques in order to calculate the light scattering …
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Influence of optical properties on two-photon fluorescence imaging in turbid samples
A numerical model was developed to simulate the effects of tissue optical properties, objective numerical aperture (N.A.), and …
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Light scattering from cells: finite-difference time-domain simulations and goniometric measurements
We have examined the light-scattering properties of inhomogeneous biological cells through a combination of theoretical simulations and …
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Near Real Time Confocal Microscopy of Cultured Amelanotic Cells: Sources of Signal, Contrast Agents and Limits of Contrast
The use of high resolution, in vivo confocal imaging for noninvasive assessment of tissue pathology may offer a clinically important …
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Penetration depth limits of in vivo confocal reflectance imaging
We present experiments to predict the maximum penetration depth at which typical biological structures in amelanotic tissue can be …
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Optical model for light distribution during transscleral cyclophotocoagulation
Transscleral cyclophotocoagulation (TSCPC) is currently performed clinically as an effective treatment for end-stage glaucoma. We …
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Finite-difference time-domain simulation of light scattering from single cells
The finite-difference time-domain (FDTD) technique is used to compute light scattering from biological cells in two dimensions. Results …
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