We develop blood flow imaging systems to study the effects of ischemic stroke on cortical perfusion and to better understand the underlying physics of dynamic light scattering.
We design high-resolution nonlinear microscopes to study the three-dimensional vascular and neuronal structures of the cortex at depths pushing the limits of optical imaging.
We simulate photon propagation through large tissue geometries in order to understand the effects of scattering and its influence on imaging depth and resolution.
We built a three-dimensional particle tracking system (TSUNAMI) capable of spatial localization far beyond the diffraction limit for use in studying molecular transport dynamics.
We combine imaging techniques to simultaneously track multiple hemodynamic parameters to study the effects of ischemic stroke on the cortex.
We utilize optical coherence tomography to study neurovascular blood flow and the physics of dynamic light scattering in order to better understand our other imaging techniques.