Chronic Imaging

Subventricular zone cytogenesis provides trophic support for neural repair in a mouse model of stroke
Stroke enhances proliferation of neural precursor cells within the subventricular zone (SVZ) and induces ectopic migration of newborn …
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Reactive astrocytes facilitate vascular repair and remodeling after stroke
Brain injury causes astrocytes to assume a reactive state that is essential for early tissue protection, but how reactive astrocytes …
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Reactive astrocytes facilitate vascular repair and remodeling after stroke
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are …
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A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
Neurovascular coupling, the close spatial and temporal relationship between neural activity and hemodynamics, is disrupted in …
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Rehabilitative training interacts with ischemia-instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex
After subtotal infarcts of primary motor cortex (M1), motor rehabilitative training (RT) promotes improvements in paretic forelimb …
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Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
The photothrombotic stroke model generates localized and reproducible ischemic infarcts that are useful for studying recovery …
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Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke
We present a dual-modality imaging system combining laser speckle contrast imaging and oxygen-dependent quenching of phosphorescence to …
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Preferential stabilization of newly formed dendritic spines in motor cortex during manual skill learning predicts performance gains, but not memory endurance
Previous findings that skill learning is associated with the formation and preferential stabilization of new dendritic spines in cortex …
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Nanoelectronics enabled chronic multimodal neural platform in a mouse ischemic model

Background: Despite significant advancements of optical imaging techniques for mapping hemodynamics in small animal models, it remains …

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Chronic monitoring of vascular progression after ischemic stroke using multiexposure speckle imaging and two-photon fluorescence microscopy
Monitoring the progression of the vascular structure and cerebral blood flow (CBF) after brain injury is vital to understand the …
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