Diffuse Reflectance Imaging

Sensitivity of neural-hemodynamic coupling to alterations in cerebral blood flow during hypercapnia
The relationship between measurements of cerebral blood oxygenation and neuronal activity is highly complex and depends on both …
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Stimulus-Induced Changes in Blood Flow and 2-Deoxyglucose Uptake Dissociate in Ipsilateral Somatosensory Cortex
The present study addresses the relationship between blood flow and glucose consumption in rat primary somatosensory cortex (SI) in …
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Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia
Real-time investigation of cerebral blood flow (CBF), and oxy- and deoxyhemoglobin concentration (HbO, HbR) dynamics has been difficult …
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Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia
Normobaric hyperoxia is under investigation as a treatment for acute ischaemic stroke. In experimental models, normobaric hyperoxia …
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Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation

The cortical hemodynamic response to somatosensory stimulus is investigated at the level of individual vascular compartments using both …

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Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex
The spatial extent of the changes in oxy-hemoglobin ($\ce{HbO}$), deoxy-hemoglobin ($\ce{HbR}$), total hemoglobin concentration …
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Coupling of the cortical hemodynamic response to cortical and thalamic neuronal activity
Accurate interpretation of functional MRI (fMRI) signals requires knowledge of the relationship between the hemodynamic response and …
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Coupling of Total Hemoglobin Concentration, Oxygenation, and Neural Activity in Rat Somatosensory Cortex

Recent advances in brain imaging techniques, including functional magnetic resonance imaging (fMRI), offer great promise for …

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Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation
A simple instrument is demonstrated for high-resolution simultaneous imaging of total hemoglobin concentration and oxygenation and …
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