Imaging System

Evaluation of resonant scanning as a high-speed imaging technique for two-photon imaging of cortical vasculature
We demonstrate a simple, low-cost two-photon microscope design with both galvo-galvo and resonant-galvo scanning capabilities. We …
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Evaluation of resonant scanning as a high-speed imaging technique for two-photon imaging of cortical vasculature
Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke
We present a dual-modality imaging system combining laser speckle contrast imaging and oxygen-dependent quenching of phosphorescence to …
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Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination
Molecular trafficking within cells, tissues and engineered three-dimensional multicellular models is critical to the understanding of …
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How to Build a Laser Speckle Contrast Imaging (LSCI) System to Monitor Blood Flow
Laser Speckle Contrast Imaging (LSCI) is a simple yet powerful technique that is used for full-field imaging of blood flow. The …
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Simultaneous imaging of oxygen tension and blood flow in animals using a digital micromirror device
In this study we present a novel imaging method that combines high resolution cerebral blood flow imaging with a highly flexible map of …
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Microvascular oxygen quantification using two-photon microscopy
An instrument is demonstrated that is capable of three-dimensional (3D) vasculature imaging and $p_{O_2}$ quantification with high …
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Robust flow measurement with multi-exposure speckle imaging
Laser Speckle Contrast Imaging (LSCI) is a minimally invasive full field optical technique used to generate blood flow maps with high …
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Frequency-domain wide-field laser Doppler in vivo imaging
We present a new instrument, based on a low-frame-rate (8Hz) CCD camera used in a heterodyne optical-mixing configuration, that can …
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Heterodyne detection of multiply scattered monochromatic light with a multipixel detector
A new technique is presented for measuring the spectral broadening of light that has been multiply scattered from scatterers in motion. …
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Laminar optical tomography: demonstration of millimeter-scale depth-resolved imaging in turbid media
Laminar optical tomography (LOT) is a new technique that combines the advantages of diffuse optical tomography image reconstruction and …
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