Laser Doppler Flowmetry

Thrombotic distal middle cerebral artery occlusion produced by topical FeCl$_3$ application: A novel model suitable for intravital microscopy and thrombolysis studies
Intravital or multiphoton microscopy and laser-speckle imaging have become popular because they allow live monitoring of several …
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Cortical blood flow assessment with frequency-domain laser Doppler microscopy
We report the assessment of cerebral blood flow (CBF) changes with a wide-field laser Doppler imager based on a CCD camera detection …
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Frequency-domain wide-field laser Doppler in vivo imaging
We present a new instrument, based on a low-frame-rate (8Hz) CCD camera used in a heterodyne optical-mixing configuration, that can …
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Pronounced hypoperfusion during spreading depression in mouse cortex
We studied unique cerebral blood flow (CBF) responses to cortical spreading depression in mice using a novel two-dimensional CBF …
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Mouse model of microembolic stroke and reperfusion

Background and Purpose: To test the role of fibrinolysis in stroke, we used a mouse model in which preformed 2.5- to 3-µm-diameter …

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Laser Speckle Flowmetry for the Study of Cerebrovascular Physiology in Normal and Ischemic Mouse Cortex
Laser speckle flowmetry (LSF) is useful to assess noninvasively two-dimensional cerebral blood flow (CBF) with high temporal and …
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