LSCI

Continuous blood flow visualization with laser speckle contrast imaging during neurovascular surgery

Significance: Laser speckle contrast imaging (LSCI) has emerged as a promising tool for intraoperative cerebral blood flow (CBF) …

PDF DOI Cite medRxiv
Continuous blood flow visualization with laser speckle contrast imaging during neurovascular surgery
Dynamics of isoflurane-induced vasodilation and blood flow of cerebral vasculature revealed by multi-exposure speckle imaging

Background: Anesthetized animal models are used extensively during neurophysiological and behavioral studies despite systemic effects …

PDF DOI Cite bioRxiv LaTeX
Reactive astrocytes facilitate vascular repair and remodeling after stroke
Brain injury causes astrocytes to assume a reactive state that is essential for early tissue protection, but how reactive astrocytes …
PDF DOI Cite
Reactive astrocytes facilitate vascular repair and remodeling after stroke
Mechanobiological conditioning of mesenchymal stem cells for enhanced vascular regeneration
Using endogenous mesenchymal stem cells for treating myocardial infarction and other cardiovascular conditions typically results in …
PDF DOI Cite bioRxiv
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are …
PDF DOI Cite
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Effect of vascular structure on laser speckle contrast imaging
Laser speckle contrast imaging (LSCI) is a powerful tool for non-invasive, real-time imaging of blood flow in tissue. However, the …
PDF DOI Cite bioRxiv
Peripheral electrical stimulation augments cerebral collateral circulation if performed within a critical time window
Ischemic stroke is one of the leading causes of death and disability in the world. Recent advances in acute stroke care have …
DOI Cite
Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
Neurovascular coupling, the close spatial and temporal relationship between neural activity and hemodynamics, is disrupted in …
PDF DOI Cite bioRxiv
Rehabilitative training interacts with ischemia-instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex
After subtotal infarcts of primary motor cortex (M1), motor rehabilitative training (RT) promotes improvements in paretic forelimb …
PDF DOI Cite
Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
The photothrombotic stroke model generates localized and reproducible ischemic infarcts that are useful for studying recovery …
PDF DOI Cite