LSCI

Mechanobiological conditioning of mesenchymal stem cells for enhanced vascular regeneration
Using endogenous mesenchymal stem cells for treating myocardial infarction and other cardiovascular conditions typically results in …
PDF DOI Cite bioRxiv
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are …
PDF DOI Cite
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Effect of vascular structure on laser speckle contrast imaging
Laser speckle contrast imaging (LSCI) is a powerful tool for non-invasive, real-time imaging of blood flow in tissue. However, the …
PDF DOI Cite bioRxiv
Peripheral electrical stimulation augments cerebral collateral circulation if performed within a critical time window
Ischemic stroke is one of the leading causes of death and disability in the world. Recent advances in acute stroke care have …
DOI Cite
Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
Neurovascular coupling, the close spatial and temporal relationship between neural activity and hemodynamics, is disrupted in …
PDF DOI Cite bioRxiv
Rehabilitative training interacts with ischemia-instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex
After subtotal infarcts of primary motor cortex (M1), motor rehabilitative training (RT) promotes improvements in paretic forelimb …
PDF DOI Cite
Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
The photothrombotic stroke model generates localized and reproducible ischemic infarcts that are useful for studying recovery …
PDF DOI Cite
Awake Mouse Imaging: From Two-Photon Microscopy to Blood Oxygen–Level Dependent Functional Magnetic Resonance Imaging

Background: Functional magnetic resonance imaging (fMRI) in awake behaving mice is well positioned to bridge the detailed …

PDF DOI Cite
Awake Mouse Imaging: From Two-Photon Microscopy to Blood Oxygen–Level Dependent Functional Magnetic Resonance Imaging
Extracellular Vimentin/VWF (von Willebrand Factor) Interaction Contributes to VWF String Formation and Stroke Pathology

Background and Purpose: VWF (von Willebrand factor) strings mediate spontaneous platelet adhesion in the vascular lumen, which may lead …

PDF DOI Cite
Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke
We present a dual-modality imaging system combining laser speckle contrast imaging and oxygen-dependent quenching of phosphorescence to …
PDF DOI Cite LaTeX