LSCI

Sensitivity of neural-hemodynamic coupling to alterations in cerebral blood flow during hypercapnia
The relationship between measurements of cerebral blood oxygenation and neuronal activity is highly complex and depends on both …
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Stimulus-Induced Changes in Blood Flow and 2-Deoxyglucose Uptake Dissociate in Ipsilateral Somatosensory Cortex
The present study addresses the relationship between blood flow and glucose consumption in rat primary somatosensory cortex (SI) in …
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Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia
Real-time investigation of cerebral blood flow (CBF), and oxy- and deoxyhemoglobin concentration (HbO, HbR) dynamics has been difficult …
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Efficient Processing of Laser Speckle Contrast Images
Though laser speckle contrast imaging enables the measurement of scattering particle dynamics with high temporal resolution, the …
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Robust flow measurement with multi-exposure speckle imaging
Laser Speckle Contrast Imaging (LSCI) is a minimally invasive full field optical technique used to generate blood flow maps with high …
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Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia
Normobaric hyperoxia is under investigation as a treatment for acute ischaemic stroke. In experimental models, normobaric hyperoxia …
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Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex
In the light of accumulating evidence for the occurrence of spontaneous cortical spreading depression and peri-infarct depolarizations …
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Vasoconstrictive neurovascular coupling during focal ischemic depolarizations
Ischemic depolarizing events, such as repetitive spontaneous periinfarct spreading depolarizations (PIDs), expand the infarct size …
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Evaluation of laser speckle flowmetry for imaging cortical perfusion in experimental stroke studies: quantitation of perfusion and detection of peri-infarct depolarisations
Laser speckle imaging of the exposed cerebral cortex allows detailed examination of the time course and topography of perfusion under …
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Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex
The spatial extent of the changes in oxy-hemoglobin ($\ce{HbO}$), deoxy-hemoglobin ($\ce{HbR}$), total hemoglobin concentration …
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