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Reactive astrocytes facilitate vascular repair and remodeling after stroke
Brain injury causes astrocytes to assume a reactive state that is essential for early tissue protection, but how reactive astrocytes …
Michael Williamson
,
Cathleen Joy Fuertes
,
Andrew Dunn
,
Michael Drew
,
Theresa Jones
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A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are …
Michael Williamson
,
Ronald Franzen
,
Cathleen Joy Fuertes
,
Andrew Dunn
,
Michael Drew
,
Theresa Jones
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Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
Neurovascular coupling, the close spatial and temporal relationship between neural activity and hemodynamics, is disrupted in …
Fei He
,
Colin Sullender
,
Hanlin Zhu
,
Michael Williamson
,
Xue Li
,
Zhengtuo Zhao
,
Theresa Jones
,
Chong Xie
,
Andrew Dunn
,
Lan Luan
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bioRxiv
Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
The photothrombotic stroke model generates localized and reproducible ischemic infarcts that are useful for studying recovery …
Taylor Clark
,
Colin Sullender
,
S. M. Shams Kazmi
,
Brittany Speetles
,
Michael Williamson
,
Daniella Palmberg
,
Andrew Dunn
,
Theresa Jones
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Intraoperative multi-exposure speckle imaging of cerebral blood flow
Multiple studies have demonstrated that laser speckle contrast imaging (LSCI) has high potential to be a valuable cerebral blood flow …
Lisa Richards
,
S. M. Shams Kazmi
,
Katherine Olin
,
James Waldron
,
Andrew Dunn
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Evaluating multi-exposure speckle imaging estimates of absolute autocorrelation times
Multi-exposure speckle imaging (MESI) is a camera-based flow-imaging technique for quantitative blood-flow monitoring by mapping the …
S. M. Shams Kazmi
,
Rebecca Wu
,
Andrew Dunn
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Flux or speed? Examining speckle contrast imaging of vascular flows
Speckle contrast imaging enables rapid mapping of relative blood flow distributions using camera detection of back-scattered laser …
S. M. Shams Kazmi
,
Ehssan Faraji
,
Mitchell Davis
,
Yu-Yen Huang
,
Xiaojing Zhang
,
Andrew Dunn
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Expanding applications, accuracy, and interpretation of laser speckle contrast imaging of cerebral blood flow
Laser speckle contrast imaging (LSCI) provides a rapid characterization of cortical flow dynamics for functional monitoring of the …
S. M. Shams Kazmi
,
Lisa Richards
,
Christian Schrandt
,
Mitchell Davis
,
Andrew Dunn
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Chronic monitoring of vascular progression after ischemic stroke using multiexposure speckle imaging and two-photon fluorescence microscopy
Monitoring the progression of the vascular structure and cerebral blood flow (CBF) after brain injury is vital to understand the …
Christian Schrandt
,
S. M. Shams Kazmi
,
Theresa Jones
,
Andrew Dunn
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Optimization of camera exposure durations for multi-exposure speckle imaging of the microcirculation
Improved Laser Speckle Contrast Imaging (LSCI) blood flow analyses that incorporate inverse models of the underlying laser-tissue …
S. M. Shams Kazmi
,
Satyajit Balial
,
Andrew Dunn
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