Neurovascular Coupling

Measurements and Modeling of Transient Blood Flow Perturbations Induced by Brief Somatosensory Stimulation
Proper interpretation of BOLD fMRI and other common functional imaging methods requires an understanding of neurovascular coupling. We …
PDF DOI Cite
Sensitivity of neural-hemodynamic coupling to alterations in cerebral blood flow during hypercapnia
The relationship between measurements of cerebral blood oxygenation and neuronal activity is highly complex and depends on both …
PDF DOI Cite
Stimulus-Induced Changes in Blood Flow and 2-Deoxyglucose Uptake Dissociate in Ipsilateral Somatosensory Cortex
The present study addresses the relationship between blood flow and glucose consumption in rat primary somatosensory cortex (SI) in …
PDF DOI Cite
Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation

The cortical hemodynamic response to somatosensory stimulus is investigated at the level of individual vascular compartments using both …

PDF DOI Cite
Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex
The spatial extent of the changes in oxy-hemoglobin ($\ce{HbO}$), deoxy-hemoglobin ($\ce{HbR}$), total hemoglobin concentration …
PDF DOI Cite
Coupling of the cortical hemodynamic response to cortical and thalamic neuronal activity
Accurate interpretation of functional MRI (fMRI) signals requires knowledge of the relationship between the hemodynamic response and …
PDF DOI Cite
Laser Speckle Flowmetry for the Study of Cerebrovascular Physiology in Normal and Ischemic Mouse Cortex
Laser speckle flowmetry (LSF) is useful to assess noninvasively two-dimensional cerebral blood flow (CBF) with high temporal and …
PDF DOI Cite
Coupling of Total Hemoglobin Concentration, Oxygenation, and Neural Activity in Rat Somatosensory Cortex

Recent advances in brain imaging techniques, including functional magnetic resonance imaging (fMRI), offer great promise for …

PDF DOI Cite
Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation
A simple instrument is demonstrated for high-resolution simultaneous imaging of total hemoglobin concentration and oxygenation and …
PDF DOI Cite