Stroke

Mapping fast tissue dynamics with long camera exposures via intensity modulation
Measuring fast dynamic processes with dynamic light scattering over wide fields of view is critical for applications ranging from blood …
PDF DOI Cite SI
12/15-Lipooxygenase inhibition reduces microvessel constriction and microthrombi after subarachnoid hemorrhage in mice
The study investigates the role of 12/15-Lipooxygenase (12/15-LOX) in microvessel constriction and microthrombi formation following …
PDF
Subventricular zone cytogenesis provides trophic support for neural repair in a mouse model of stroke
Stroke enhances proliferation of neural precursor cells within the subventricular zone (SVZ) and induces ectopic migration of newborn …
PDF DOI Cite bioRxiv
All fiber-based illumination system for multi-exposure speckle imaging
Monitoring blood flow is critical to treatment efficacy in many surgical settings. Laser speckle contrast imaging (LSCI) is a simple, …
PDF DOI Cite
Reactive astrocytes facilitate vascular repair and remodeling after stroke
Brain injury causes astrocytes to assume a reactive state that is essential for early tissue protection, but how reactive astrocytes …
PDF DOI Cite
Reactive astrocytes facilitate vascular repair and remodeling after stroke
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are …
PDF DOI Cite
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Peripheral electrical stimulation augments cerebral collateral circulation if performed within a critical time window
Ischemic stroke is one of the leading causes of death and disability in the world. Recent advances in acute stroke care have …
DOI Cite
Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
Neurovascular coupling, the close spatial and temporal relationship between neural activity and hemodynamics, is disrupted in …
PDF DOI Cite bioRxiv
Rehabilitative training interacts with ischemia-instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex
After subtotal infarcts of primary motor cortex (M1), motor rehabilitative training (RT) promotes improvements in paretic forelimb …
PDF DOI Cite
Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
The photothrombotic stroke model generates localized and reproducible ischemic infarcts that are useful for studying recovery …
PDF DOI Cite