Stroke

All fiber-based illumination system for multi-exposure speckle imaging
Monitoring blood flow is critical to treatment efficacy in many surgical settings. Laser speckle contrast imaging (LSCI) is a simple, …
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Subventricular zone cytogenesis provides trophic support for neural repair
Stroke enhances proliferation of neural precursor cells within the subventricular zone (SVZ) and induces ectopic migration of newborn …
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Reactive astrocytes facilitate vascular repair and remodeling after stroke
Brain injury causes astrocytes to assume a reactive state that is essential for early tissue protection, but how reactive astrocytes …
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Reactive astrocytes facilitate vascular repair and remodeling after stroke
A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are …
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A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke
Peripheral electrical stimulation augments cerebral collateral circulation if performed within a critical time window
Ischemic stroke is one of the leading causes of death and disability in the world. Recent advances in acute stroke care have …
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Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
Neurovascular coupling, the close spatial and temporal relationship between neural activity and hemodynamics, is disrupted in …
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Rehabilitative training interacts with ischemia-instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex
After subtotal infarcts of primary motor cortex (M1), motor rehabilitative training (RT) promotes improvements in paretic forelimb …
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Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
The photothrombotic stroke model generates localized and reproducible ischemic infarcts that are useful for studying recovery …
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Extracellular Vimentin/VWF (von Willebrand Factor) Interaction Contributes to VWF String Formation and Stroke Pathology

Background and Purpose: VWF (von Willebrand factor) strings mediate spontaneous platelet adhesion in the vascular lumen, which may lead …

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Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke
We present a dual-modality imaging system combining laser speckle contrast imaging and oxygen-dependent quenching of phosphorescence to …
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